priors.science/reviews/polyphenols-antioxidants

Polyphenols and Antioxidants

The current evidence on 15 claims, ordered from most established to most contested. Each score is the panel’s evidence certainty — how firmly the literature supports the claim as stated.

15claims tracked
196primary papers reviewed
5 Jul 2026latest evidence review
Weeklyre-scored against new papers
4 Established · 5 Likely · 6 Uncertain · 0 Doubtful  |  four-reviewer panel · PICO Framework
SignalClaimStandingEvidence certaintyCorpus
StableVitamin E and cardiovascular eventsSupEstablished87%20
StablePolyphenol bioavailability is lowBioEstablished85%14
StableBeta-carotene raises smoker lung cancer riskCancEstablished85%14
StableCocoa flavanols lower blood pressureCVEstablished85%20
StableVitamin C and common coldSupLikely81%20
StableAntioxidant supplements and mortalitySupLikely80%14
StableCocoa flavanols improve endothelial functionCVLikely78%14
StableGut microbiota metabolise polyphenolsBioLikely77%14
StableFlavonoids lower cardiovascular disease mortalityCVLikely73%20
StablePolyphenols and insulin sensitivityMetUncertain60%20
StableFlavonoids and cognitive declineCogUncertain55%14
StableBerry anthocyanins and memoryCogUncertain53%14
StablePolyphenols and colorectal cancer riskCancUncertain51%14
StableResveratrol and glycaemic control type 2 diabetesMetUncertain50%14
StableGreen tea catechins and body weightMetUncertain47%14
Standing — what the evidence certainty means
Established≥ 85%Strong, consistent evidence. Unlikely to change.
Likely65–84%Well supported, with some gaps or indirect evidence.
Uncertain40–64%Mixed or limited evidence. Genuinely open.
Doubtful15–39%Little support; the weight of evidence leans against it.
Refuted< 15%The evidence contradicts it — confidently false as stated.
Recent signal
strengthenedNew evidence raised the certainty since the last review.
weakenedNew evidence lowered the certainty since the last review.
newA claim added to the review recently.
StableNo recent change to the standing.
Standing, evidence certainty and corpus are always shown. The study behind each move, why it moved, and the sceptic’s challenge are delivered to subscribers.
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