Priors rates this Likely — 76 out of 100, updated weekly. Probably — but it is not fully settled. On the claim that carbapenemase-producing organisms (CPO) including KPC, OXA-48, NDM, and VIM enzymes are globally distributed, with plasmid-mediated horizontal transfer the dominant mechanism of carbapenem resistance spread, its four-agent AI review panel weighs 6 primary peer-reviewed studies.
How we got this answer. Priors runs each claim through a panel of four AI agents, each acting as a specialist expert reviewer. They read the published, peer-reviewed studies behind the question, judge how strong, consistent and reliable the evidence is, and turn that judgment into a single rating from 0 to 100 — refreshed every week as new studies appear, so it reflects where the evidence stands today, not a one-off verdict.
The traceable studies behind this rating — and the panel’s single strongest counter-argument to it — are in Priors’ full Antimicrobial Resistance Novel Antibiotics review.